ABOUT GLP-1 INJECTIONS
GLP-1 receptor agonists such as Semaglutide (Ozempic®, Wegovy®) and Tirzepatide (Mounjaro®, Zepbound®) are advanced injectable medications used for weight management, blood sugar control, and metabolic health.
They work by:
- Mimicking a natural gut hormone (GLP-1) that helps regulate blood sugar and appetite.
- Slowing gastric emptying, promoting early satiety, and reducing food cravings.
- Improving insulin sensitivity and lowering glucose levels.
When used under medical supervision with a balanced diet and physical activity, these medications are highly effective for long-term weight loss, improved metabolism, and cardiovascular health.
PRE-TREATMENT CARE
Before Starting GLP-1 Injections
- Discuss with your provider:
- Any history of thyroid disorders, pancreatitis, gallbladder disease, or gastrointestinal conditions.
- Current medications, including insulin, oral diabetes medications, or weight loss supplements, to avoid interactions.
- Any family history of medullary thyroid carcinoma (MTC) or MEN2 (Multiple Endocrine Neoplasia type 2) — GLP-1s are contraindicated in these cases.
- Fasting blood tests (glucose, A1C, liver/kidney panel, lipids) may be recommended before starting.
- Establish baseline weight, BMI, and waist measurements for tracking progress.
Day Before and Day of Injection
- Eat normally — fasting is not required.
- Stay hydrated, as dehydration can worsen nausea.
- Avoid alcohol and greasy, high-fat meals before your injection.
- Wear comfortable clothing that allows easy access to your abdomen, thigh, or upper arm (injection sites).
- If you are prone to nausea, your provider may recommend taking your injection with a small meal or in the evening.
POST-INJECTION CARE
Immediately After Injection
- Mild redness, itching, or tenderness at the injection site is normal and should resolve within a few hours.
- Do not rub or massage the injection area.
- Rotate injection sites each week (abdomen, thigh, arm) to avoid irritation or bruising.
- If bleeding occurs, apply gentle pressure with a clean gauze — do not use alcohol directly afterward.
Common Early Side Effects (First Few Weeks)
Mild side effects are common as your body adjusts, especially during dose increases:
- Nausea, fullness, bloating, or mild stomach upset
- Constipation or diarrhea
- Decreased appetite
- Fatigue or mild headache
These typically subside within a few days to weeks.
Tips to Minimize Side Effects:
- Eat smaller, more frequent meals (5–6 light meals per day).
- Eat slowly and stop when you feel full.
- Avoid greasy, fried, or heavy foods.
- Drink plenty of water throughout the day (at least 64 oz).
- Increase fiber intake (vegetables, whole grains) to prevent constipation.
- Avoid lying down for 1 hour after eating.
Dietary and Lifestyle Recommendations
- Prioritize protein in every meal to preserve lean muscle.
- Include fresh vegetables, fruits, and complex carbohydrates for balanced nutrition.
- Avoid carbonated beverages and high-sugar drinks.
- Limit alcohol, which can worsen nausea and affect blood sugar.
- Exercise regularly — aim for 150 minutes per week of combined cardio and strength training.
- Get 7–8 hours of sleep each night to support metabolic balance.
ONGOING CARE AND MONITORING
- Your provider will guide you through a gradual dose escalation to minimize side effects.
- Do not adjust your dose without medical guidance.
- Weigh yourself once weekly at the same time of day to track progress.
- Monitor hydration — signs of dehydration include dizziness, dark urine, or dry mouth.
- Report persistent nausea, vomiting, or abdominal pain immediately — these may indicate rare side effects such as pancreatitis or gallbladder irritation.
- Schedule follow-up visits every 4–6 weeks for evaluation, dosing adjustments, and progress tracking.
RESULTS AND MAINTENANCE
- Most patients begin noticing reduced appetite and early weight loss within 2–4 weeks.
- Steady, healthy weight reduction continues over 3–6 months, depending on dosage and lifestyle adherence.
- Full metabolic and body composition improvements occur over 6–12 months of consistent therapy.
- Once goal weight is achieved, your provider may recommend a maintenance dose to sustain results.
WHEN TO CALL OUR OFFICE
Contact Specialty Wellness & MedSpa immediately at 469-442-4442 or seek medical attention if you experience:
- Persistent or severe abdominal pain (especially radiating to the back)
- Severe nausea or vomiting that prevents eating or hydration
- Signs of pancreatitis or gallbladder disease: severe pain, fever, jaundice (yellowing of skin or eyes)
- Allergic reaction: swelling, rash, or difficulty breathing
- Severe constipation lasting more than 5 days
- Dizziness, confusion, or rapid heart rate
Have Questions?
If you have any questions or concerns about your GLP-1 injection therapy, please do not hesitate to call Specialty Wellness & MedSpa at 469-442-4442.
Our medical team will support you every step of the way to ensure your safety, success, and confidence in your weight management journey.
